Cryo Bio System

With over 30 years of experience, Cryo Bio System is a global leader in life science and biodiversity, offering innovative, high-security cryopreservation solutions for biological samples. Headquartered in France, the company’s comprehensive product range caters to scientists and physicians, ensuring ultra-low temperature freezing and long-term storage quality. The company’s unique high-security approach guarantees unparalleled safety. Cryo Bio System operates across 70 countries through five subsidiaries and a robust distributor network.

CBS™ Digitcool®Automated Cryopreservation Solutions
The CBS Digitcool® series provides a versatile array of controlled-rate freezers catering to diverse cryopreservation requirements. The line includes:
Digitcool®: A robust solution for large cryopreservation centers, accommodating high-security straws, cryogenic vials, glass ampoules, and blood bags, with custom rack options available.

Mini-Digitcool®: Tailored for users with moderate freezing needs, such as tissue banks and cellular therapy centers, it supports a variety of storage formats including straws, tubes, and bags.

Micro-Digitcool®: A compact freezer preferred by tissue and cord blood banks, cellular culture facilities, and clinical trials, offering efficient storage for straws, tubes, and bags.

Nano-Digitcool®: Designed for daily use in Assisted Reproductive Technology centers, this compact freezer is ideal for smaller-scale, yet critical, cryopreservation needs.
Each unit in the Digitcool® line is meticulously crafted to ensure reliability, consistency, and performance for the critical task of biological sample preservation.
Single unit
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CBS™ Goblets and Visotubes

$12.99 – $84.99
Cryo Bio System™ (CBS) Goblets and Visotubes maximize your cryotank’s limited space by offering a unique spatial and colour-coded organization system for storing biological samples.
5 goblets/pkg or 10 visotubes/pkg

Goblets and Visotubes come in a variety of colours, shapes and sizes, allowing for easy sample identification

Goblets hold 12 Visotubes and can hold a maximum of 168 CBS High Security Vitrification Straws, or 240 CBS High Security 0.3 ml or 0.5 ml Straws
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CBS™ High Security Sperm Straw

$13.99 – $188.99
The CBS™ High Security Sperm Straw with braided plug is designed for the cryopreservation of human sperm. Made from a transparent ionomeric resin that is biocompatible and chemically inert, the straw’s high surface to volume ratio provides improved and homogenous heat exchange over the total volume of the straw. Available in two sizes, High Security Sperm Straws are designed for use with SYMS-type sealers. This fully closed vitrification system eliminates any possibility of cross-contamination to the specimen or its environment.
20 or 100 straws (packaged in blisters of 5)

High security closed system vitrification device

CBS™ 0.3 ml straw features two compartments separated by a white plug: 1) compartment containing semen with a capacity of 0.3 ml, and 2) compartment that accommodates the coloured identification rod and is used for holding when handling liquid nitrogen

CBS™ 0.5 ml straw features the same technical specifications as the 0.3 ml straw, but has a capacity of 0.5 ml and boasts a coloured external plug surface

For large-scale application (for example, sperm banks), straws are filled with PACE, MAPI or DIVA automated filling and sealing machines

Sealing straws with a CBS SYMS sealer ensures an impervious and high security seal

Leak-proof and shatter-proof, guaranteed all the way down to LN2 temperatures

Mechanically resistant to pressures of up to 150 kg/cm²and indestructible under normal conditions of use

Compatible with all nitrogen freezers and containers, both liquid and vapor phase as well as ultra-low temperature mechanical freezers

Requires a sterile filling nozzle and a micro-aspirator or a syringe equipped with a special connector are used to manually fill straws

CE-marked medical device and FDA 510 (k) approved
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CBS™ High Security Sterile Embryo and Sperm Straw

$1.00
The CBS™ High Security Embryo and Sperm Straw with braided plug is designed for the long-term cryopreservation of human sperm and embryos. Made from a transparent ionomeric resin that is biocompatible and chemically inert, these high-quality straws have a high surface to volume ratio for improved and homogenous heat exchange over the total volume of the straw. The fully closed vitrification system eliminates any possibility of cross-contamination to the specimen or its environment.
20 straws (4 packs of 5 blisters each)

High security closed system vitrification device

Straws have two distinct compartments separated by the braided plug that allows for controlled loading and extracting

Tamper-proof top compartment for placement of a coloured identification rod to guarantee sample traceability

Leak-proof and shatter-proof, guaranteed all the way down to LN2 temperatures

Mechanically resistant to pressures of up to 150 kg/cm²and indestructible under normal conditions of use

Sealing straws with a CBS™ SYMS sealer assures an impervious and high security seal

Compatible with all nitrogen freezers and containers, both liquid and vapor phase as well as ultra-low temperature mechanical freezers

Requires a sterile filling nozzle and a micro-aspirator or a syringe equipped with a special connector are used to manually fill straws

CE-marked medical device and FDA 510 (k) approved
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CBS™ High Security Tube

$107.99
CBS™ High Security Tubes are a unique fully secured system for storage of biological materials in liquid nitrogen. Once sealed, the tube eliminates any concerns related to cross-contamination and sample degradation from oxidation and evaporation. The High Security resin material is compatible with cryogenic storage temperatures from -80°C to LN2. The tubes are designed to function with the CBS™ SYMS III Sealer.
20 sterile tubes

High security closed system vitrification device

Ideal for the cryopreservation of biological samples: biobanking; preservation of fertility (ovarian and testicular tissue, and sperm); biological tissue for clinical phase or research; biological samples for blood banks and blood transfusion centers; cell and genetic therapy (clinical phase and therapeutic applications); and the packaging of vaccines and heat-sensitive drugs

Validated as leak-proof and shatter-proof in all cryogenic temperatures including temperatures as low as LN2 liquid phase

Indestructible under normal conditions of use

Traceable with coloured inserts, 2D data matrix coded inserts, and compatible with cryoresistant labels

Compatible with cryogenic storage temperatures from -80°C to LN2

Compatible with common storage systems, manual and automatic filling systems, programmable freezers and liquid nitrogen, vapor phase and mechanical freezers

CE-marked medical device with Class II/a certification, appropriate for clinical phase trials and therapeutic applications
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CBS™ High Security Vitrification Straws

$106.99
CBS™ High Security Vitrification (HSV) Straws are designed for the vitrification of human oocytes and embryos (all stages). The straw is made from transparent biocompatible ionomeric resin, making it secure, durable, and simple to use. The physical properties and method of sealing HSV straws guarantees that they remain sealed when immersed and stored in liquid nitrogen. The fully closed vitrification system eliminates any possibility of cross-contamination.
4 individual peel-off blisters / pack

High security closed system vitrification device

Composed of three distinct parts: a High Security ultra-thin outer straw, featuring a pre-sealed weighted end and flared opening; a capillary tube with pre-formed, fully clear gutter co-injected with its coloured identification rod; and a blue introduction device

One-step opening and retrieval

Designed for use with CBS™ SYMS Sealers for perfect sealing, and fully compatible with CBS™ storage products

Packaging designed to provide a "double sterile barrier", facilitating transfers into aseptic working areas

Compatible with all nitrogen freezers and containers, both liquid and vapor phase, as well as ultra-low temperature mechanical freezers

International Standards Compliance CE, FDA 510 (k) cleared
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CBS™ ID Jackets for High Security Sperm Straws

$20.99

CBS™ ID Jackets are designed for use with CBS™ 0.5 ml High Security Sperm Straws. These external identification sleeves can be identified with the application of a custom label or written on directly with a cryo-safe marker. ID Jackets become secure once the straw is sealed for reliable tracking of straws in long-term storage.
50 jackets / pkg

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CBS™ Micro-Aspirator

$285.99
The CBS™ Micro-aspirator device is used for manually filling straws during cryopreservation. It eliminates the risk of contamination and is compatible with all CBS™ straws.
Single device

Eliminates risk of contamination while filling straws

Compatible with all CBS™ straws

No specific maintenance required
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CBS™ SYMS I Sealer

$1.00
The Cryo Bio System™ (CBS) SYMS I Sealer is a tabletop device specifically designed to seal CBS High Security straws. Crafted with ionomeric resin, this sealer is highly reliable and durable, requiring minimal maintenance and ensuring optimal operation in the long run. The SYMS I can effectively seal 0.3 ml and 0.5 ml CBS High Security straws, as well as CBS High Security Vitrification straws. These straws are integral components of the CBS closed cryopreservation system, and the SYMS I Sealer ensures a secure seal, contributing to the system's overall safety and effectiveness. The sealer provides users with flexibility in operation, as it can be activated by either a push-button or a foot switch, depending on the user's preference. This user-friendly functionality makes the SYMS I Sealer a valuable asset in laboratories and facilities that use the CBS cryopreservation system.
Single unit

Two options to best suit your workflow: push-button or foot switch

Requires only 5 minutes per day for start-up, maintenance, and shut-down procedures

Easily cleaned with ethanol or a non-corrosive decontaminant fluid
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CBS™ SYMS III Sealer for High Security straws and tubes
The Cryo Bio System™ (CBS) SYMS III Sealer is a bench top unit designed to thermally seal all CBS™ High Security products, including CBS™ High Security 0.3 ml, 0.5 ml and 2 ml straws, CBS™ High Security Tubes, and CBS™ High Security Vitrification straws. Using an automatic detection system, the unit uses pre-set specific combinations of seal temperatures, time and jaw positions for each CBS device. Due to its compact size, the SYMS III can be used in a variety of locations, including on the lab bench, under laminar flow, or even in field operations.
Single unit

Multilingual interface (French, English, Spanish and Chinese) + 4 optional languages

Laboratory glove-compatible colour touch screen

Machine cycle display: pre-heating, ready status and sealing in progress

Two sealing modes: automatic detection or operator-controlled via the touch screen

Fault signal with messages and alarms

Display and tracking of maintenance modes

Easy to clean and service
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CBS™ Weighted ID Rods for High Security Sperm Straws

$7.99

CBS™ Weighted ID Rods are designed for use with CBS™ 0.3 ml High Security Sperm Straws. Thee rods provide internal colour-coding for easy sample identification, and are weighted to prevent filled straws from floating when immersed in liquid nitrogen.
10 rods / pkg

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